Tempus Reports First Quarter 2026 Results

via Business Wire
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Tempus AI, Inc. (NASDAQ: TEM), a technology company leading the adoption of AI to advance precision medicine and patient care, today reported financial results for the quarter ended March 31, 2026.

  • Revenue of $348.1 million, up 36.1% year-over-year
  • Diagnostics revenue of $261.1 million, representing 34.7% growth year-over-year, driven by Oncology volume growth of 28%
  • MRD volume was ~6,500 tests in Q1 2026, up ~500% year-over-year
  • Data and Applications revenue of $87.0 million, representing 40.5% year-over-year growth, with Insights (data licensing and modeling) growing 44.1%
  • $643.8 million in cash and marketable securities as of March 31, 2026
  • Increasing revenue guidance to $1.59 to $1.60 billion for 2026 and expect full year 2026 Adjusted EBITDA of approximately $65 million

“Our strong financial and operational performance this quarter underscores the accelerating demand for our AI-driven diagnostic platform and the immense value of our multimodal data and corresponding AI models,” said Eric Lefkofsky, Founder and CEO of Tempus. “We continue to see strong momentum as we deploy more sophisticated algorithms across our platform, driving 36% revenue growth year-over-year, with particular strength in our Oncology diagnostic business and data and modeling business.”

First Quarter Summary Results

  • Revenue increased 36.1% year-over-year to $348.1 million.
  • Diagnostics generated $261.1 million of revenue, representing 34.7% year-over-year growth, driven by Oncology volume growth of 28% and Hereditary volume growth of 54% (7% growth when accounting for Ambry's 2025 pre-acquisition volumes given February's closing date).
  • Data and Applications revenue generated $87.0 million of revenue, representing 40.5% year-over-year growth, with Insights growing 44.1%.
  • Gross profit increased 43.1% year-over-year to $222.0 million, led by growth in Data and Applications.
  • Net loss was ($125.9 million), which included $56.3 million of stock compensation expense and related employer payroll taxes in the first quarter and $32.3 million in unrealized losses on marketable securities, compared to a net loss of ($68.0 million) in the first quarter of 2025 and a net loss of ($54.2 million) in the fourth quarter of 2025.
  • Adjusted EBITDA was ($2.8 million), compared to ($16.2 million) in the first quarter of 2025 and $12.9 million in the fourth quarter of 2025.

Recent Operational Highlights

  • Established a multi-year, strategic collaboration with Merck to accelerate biomarker discovery and development by leveraging Tempus’ multimodal data and Lens analytical platform.
  • Expanded our collaboration with Gilead to provide enterprise-wide access to our AI-driven Lens platform and multimodal datasets, aimed at advancing their oncology pipeline through real-world evidence and AI-driven insights.
  • Selected by Northwestern Medicine to expand genomic testing access to oncology patients across the health system, leveraging Tempus' full suite of DNA, RNA, liquid biopsy, and MRD tests to enable more personalized cancer care and clinical trial design.
  • Entered a multi-year strategic collaboration with NYU Langone Health, centered on a prospective observational study that uses serial molecular profiling to track cancer evolution and treatment resistance, with the goal of developing AI-powered diagnostic tools and personalized therapies.
  • Entered strategic collaboration with Blood Cancer United to develop one of the largest real-world data registries for pediatric acute myeloid leukemia, aimed at accelerating research and improving treatment options for young patients.
  • Announced study results from the ALERT trial in collaboration with Medtronic showing that Tempus’ AI-driven EHR notifications increased life-saving heart valve procedures by 40% for patients with significant disease.
  • Published a study in JCO Precision Oncology demonstrating that Tempus' advanced features including tumor-normal matching and RNA sequencing identified actionable findings in 12% of patients that were missed by standard testing.
  • Announced the launch of a first-of-its-kind pan-cancer algorithm that utilizes RNA expression data to identify Homologous Recombination Deficiency (HRD), expanding the number of patients who may benefit from PARP inhibitors beyond those identified by traditional DNA testing.

First Quarter Financial Results

 

 

Three Months Ended March 31,

 

 

 

 

 

 

2026

 

 

2025

 

 

Change

 

 

 

(in thousands, except percentages and per share amounts)

 

 

 

 

 

 

(unaudited)

 

 

 

 

Revenue

 

$

348,116

 

 

$

255,737

 

 

 

36.1

%

Gross profit

 

$

222,041

 

 

$

155,203

 

 

 

43.1

%

Loss from operations

 

$

(84,711

)

 

$

(68,689

)

 

 

23.3

%

Non-GAAP loss from operations

 

$

(11,580

)

 

$

(25,777

)

 

 

(55.1

)%

Net loss

 

$

(125,919

)

 

$

(68,037

)

 

 

85.1

%

Non-GAAP net loss

 

$

(22,612

)

 

$

(41,561

)

 

 

(45.6

)%

Adjusted EBITDA

 

$

(2,833

)

 

$

(16,174

)

 

 

82.5

%

Net loss per share, basic

 

$

(0.70

)

 

$

(0.40

)

 

 

75.0

%

Non-GAAP net loss per share, basic

 

$

(0.13

)

 

$

(0.24

)

 

 

(45.8

)%

Financial Outlook and Guidance

Tempus is increasing full year 2026 revenue guidance to $1.59 billion - $1.60 billion, which represents ~25% annual growth. We continue to expect 2026 Adjusted EBITDA to be ~$65 million.

For additional information on the quarter, including a letter from our CEO and CFO, please visit our investor relations site at investors.tempus.com.

Webcast and Conference Call Information

A conference call and webcast will begin today, May 5, 2026 after market close at 4:30 p.m. Eastern Time. Interested parties may access details at:

Conference ID: 4294068
Domestic Dial-in Number: (646) 307-1963
International Dial-in Number: (800) 715-9871
Live webcast: https://edge.media-server.com/mmc/p/rv7jv7ti

The webcast may be accessed on the company’s investor relations website at investors.tempus.com. For those unable to listen to the live webcast, a recording will be made available on the company’s website after the event and will be accessible for one year. Visit the investor relations website to find the company’s latest deck, and commentary on the quarter by Eric Lefkofsky, Founder and CEO and Jim Rogers, CFO, which will be discussed on the conference call and webcast.

Tempus Inaugural Investor Day and Webcast Details

Tempus will host its inaugural Investor Day for analysts and institutional investors on Friday, May 29, 2026.

The event will feature comprehensive presentations from several senior Tempus leaders, highlighting key developments across the company's Diagnostics and Data & Applications organizations. The live webcast of management presentations is scheduled to begin at 8:00 a.m. Central Time.

The Investor Day will be broadcast live and can be accessed through the Investor Relations section of the Tempus website under the “News & Events” tab at investors.tempus.com. Institutional investors can request in-person attendance at our Chicago headquarters by emailing investorrelations@tempus.com.

About Tempus

Tempus is a technology company advancing precision medicine through the practical application of artificial intelligence in healthcare. With one of the world’s largest libraries of multimodal data, and an operating system to make that data accessible and useful, Tempus provides AI-enabled precision medicine solutions to physicians to deliver personalized patient care and in parallel facilitates discovery, development and delivery of optimal therapeutics. The goal is for each patient to benefit from the treatment of others who came before by providing physicians with tools that learn as the company gathers more data. For more information, visit tempus.com.

Non-GAAP Financial Measures

In addition to the financial information presented in this release in accordance with accounting principles generally accepted in the United States of America (GAAP), Tempus also presents adjusted non-GAAP financial measures.

Non-GAAP gross profit is defined as GAAP gross profit, excluding stock-based compensation expense and employer payroll tax related to stock-based compensation (collectively, the “stock-based compensation adjustments”). Non-GAAP gross margin is defined as gross profit, excluding the stock-based compensation adjustments, as a percentage of revenue. Non-GAAP operating expenses are calculated as the sum of technology research and development expense, research and development expense, and selling, general and administrative expense, excluding the stock-based compensation adjustments, acquisition-related expenses, and amortization of intangibles due to acquisition. Non-GAAP loss from operations is defined as loss from operations, adjusted to exclude (i) the stock-based compensation adjustments, (ii) acquisition-related expenses, and (iii) amortization of intangibles due to acquisition. Non-GAAP net loss is defined as net loss, adjusted to exclude (i) changes in fair value of our marketable equity securities and indemnity-related holdback liabilities, (ii) the stock-based compensation adjustments, (iii) acquisition-related expenses, (iv) amortization of intangibles due to acquisition, (v) losses from equity method investments, (vi) benefit from income taxes, and (vii) amortization of deferred other income from our IP License Agreement with SB Tempus. Non-GAAP net loss per share is defined as non-GAAP net loss divided by weighted average common shares outstanding, basic and diluted.

Adjusted EBITDA is defined as net loss, adjusted to exclude (i) interest income, (ii) interest expense, (iii) depreciation and amortization, (iv) benefit from income taxes, (v) losses from equity method investments, (vi) changes in fair value of our marketable equity securities and indemnity-related holdback liabilities, (vii) the stock-based compensation adjustments, (viii) acquisition-related expenses, and (ix) amortization of deferred other income from our IP License Agreement with SB Tempus.

Tempus believes these non-GAAP financial measures are useful to investors and others because they allow for additional information with respect to financial measures used by management in its financial and operational decision-making and they may be used by institutional investors and the analyst community to help them analyze the health of Tempus’ business. In particular, Adjusted EBITDA is a key measurement used by Tempus management to make operating decisions, including those related to analyzing operating expenses, evaluating performance, and performing strategic planning and annual budgeting. However, there are a number of limitations related to the use of non-GAAP financial measures, and these non-GAAP measures should be considered in addition to, not as a substitute for or in isolation from, our financial results prepared in accordance with GAAP. Other companies, including companies in our industry, may calculate these non-GAAP financial measures differently or not at all, which reduces their usefulness as comparative measures.

Tempus does not provide guidance for net loss, the most directly comparable GAAP measure to Adjusted EBITDA, and similarly cannot provide a reconciliation between Tempus’ forecasted Adjusted EBITDA and net loss without unreasonable effort due to the unavailability of reliable estimates for certain components of net loss and the respective reconciliations. These forecasted items are not within Tempus’ control, may vary greatly between periods, and could significantly impact future financial results.

Other Key Metrics

Total Remaining Contract Value (TCV) is equal to the total potential value of signed contracts and assumes the exercise of all contract options, all discretionary opt-ins, and no early termination. Remaining TCV excludes any revenue recognized to date on these contracts or any future adjustments made to the contractual value as a result of amendments or terminations.

Net Revenue Retention compares the annual Insights product revenue generated from all customers that made an Insights purchase in one year to the annual Insights product revenue generated from the same cohort of customers in the subsequent year.

Forward Looking Statements

This press release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, about Tempus and its industry that involve substantial risks and uncertainties. All statements other than statements of historical facts contained in this press release are forward-looking statements, including, but not limited to, Tempus’ expected financial results for full year 2026; expectations concerning Tempus' collaborations and partnerships; and Tempus' growth expectations. In some cases, you can identify forward-looking statements because they contain words such as “anticipate,” “believe,” “contemplate,” “continue,” “could,” “estimate,” “expect,” “going to,” “intend,” “may,” “plan,” “potential,” “predict,” “project,” “should,” “target,” “will,” or “would” or the negative of these words or other similar terms or expressions. Tempus cautions you that the foregoing may not include all of the forward-looking statements made in this press release.

You should not rely on forward-looking statements as predictions of future events. Tempus has based the forward-looking statements contained in this press release primarily on its current expectations and projections about future events and trends that it believes may affect Tempus’ business, financial condition, results of operations and prospects. These forward-looking statements are subject to risks and uncertainties related to: the intended use of Tempus’ products and services; Tempus’ financial performance; the ability to attract and retain customers and partners; managing Tempus’ growth and future expenses; competition and new market entrants; compliance with new laws, regulations and executive actions, including any evolving regulations in the artificial intelligence space; the ability to maintain, protect and enhance Tempus’ intellectual property; the ability to attract and retain qualified team members and key personnel; the ability to repay or refinance outstanding debt, or to access additional financing; future acquisitions, divestitures or investments, including Tempus’ ability to realize the expected benefits of the acquisition of Paige AI, Ambry Genetics and Deep 6 AI; the potential adverse impact of climate change, natural disasters, health epidemics, macroeconomic conditions, trade tensions and tariffs, and war or other armed conflict, as well as risks, uncertainties, and other factors described in the section titled “Risk Factors” in Tempus’ Form 10-K for the year ended December 31, 2025, filed with the Securities and Exchange Commission (“the SEC”) on February 24, 2026, as well as in other filings Tempus may make with the SEC from time to time. In addition, any forward-looking statements contained in this press release are based on assumptions that Tempus believes to be reasonable as of this date. Tempus undertakes no obligation to update any forward-looking statements to reflect events or circumstances after the date of this press release or to reflect new information or the occurrence of unanticipated events, except as required by law.

 

Tempus AI, Inc.

CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS

(Unaudited)

(in thousands, except per share amounts)

 

 

 

Three Months Ended March 31,

 

 

 

2026

 

 

2025

 

Net revenue

 

 

 

 

 

 

Diagnostics

 

$

261,098

 

 

$

193,804

 

Data and applications(1)

 

 

87,018

 

 

 

61,933

 

Total net revenue

 

$

348,116

 

 

$

255,737

 

Cost and operating expenses

 

 

 

 

 

 

Cost of revenues, diagnostics

 

 

100,960

 

 

 

84,783

 

Cost of revenues, data and applications

 

 

25,115

 

 

 

15,751

 

Technology research and development

 

 

45,921

 

 

 

33,391

 

Research and development

 

 

48,237

 

 

 

35,874

 

Selling, general and administrative

 

 

212,594

 

 

 

154,627

 

Total cost and operating expenses

 

 

432,827

 

 

 

324,426

 

Loss from operations

 

$

(84,711

)

 

$

(68,689

)

Interest income

 

 

3,866

 

 

 

1,813

 

Interest expense

 

 

(14,341

)

 

 

(18,003

)

Other expense, net

 

 

(27,709

)

 

 

(27,455

)

Loss before benefit from income taxes

 

$

(122,895

)

 

$

(112,334

)

Benefit from income taxes

 

 

62

 

 

 

46,180

 

Losses from equity method investments

 

 

(3,086

)

 

 

(1,883

)

Net Loss

 

$

(125,919

)

 

$

(68,037

)

Net loss per share

 

 

 

 

 

 

Basic

 

$

(0.70

)

 

$

(0.40

)

Diluted

 

$

(0.71

)

 

$

(0.40

)

Weighted-average shares outstanding used to compute net loss per share

 

 

 

 

 

 

Basic

 

 

178,880

 

 

 

170,506

 

Diluted

 

 

178,964

 

 

 

170,506

 

Comprehensive Loss, net of tax

 

 

 

 

 

 

Net loss

 

$

(125,919

)

 

$

(68,037

)

Foreign currency translation adjustment

 

 

(1,810

)

 

 

4,598

 

Comprehensive loss

 

$

(127,729

)

 

$

(63,439

)

(1)

Includes related party revenue of $21,823 and $631 for the three months ended March 31, 2026 and 2025, respectively.

 

Tempus AI, Inc.

CONDENSED CONSOLIDATED BALANCE SHEETS

(Unaudited)

(in thousands, except share and per share amounts)

 

 

 

March 31, 2026

 

 

December 31, 2025

 

Assets

 

 

 

 

 

 

Current Assets

 

 

 

 

 

 

Cash and cash equivalents

 

$

521,170

 

 

$

604,787

 

Accounts receivable(1), net of allowances of $2,872 and $2,755 at March 31, 2026 and December 31, 2025, respectively

 

 

308,599

 

 

 

311,170

 

Inventory

 

 

51,831

 

 

 

51,724

 

Related party asset

 

 

11,910

 

 

 

8,785

 

Prepaid expenses and other current assets

 

 

42,530

 

 

 

40,498

 

Marketable equity securities

 

 

117,902

 

 

 

150,211

 

Total current assets

 

$

1,053,942

 

 

$

1,167,175

 

Property and equipment, net

 

 

88,593

 

 

 

89,156

 

Goodwill

 

 

470,169

 

 

 

470,211

 

Intangible assets, net

 

 

330,587

 

 

 

349,202

 

Capitalized software, net

 

 

9,505

 

 

 

6,051

 

Investments and other assets

 

 

20,530

 

 

 

21,111

 

Investment in joint venture

 

 

81,675

 

 

 

86,557

 

Related party asset, less current portion

 

 

13,090

 

 

 

16,215

 

Operating lease right-of-use assets

 

 

62,306

 

 

 

64,496

 

Restricted cash

 

 

4,694

 

 

 

4,664

 

Total Assets

 

$

2,135,091

 

 

$

2,274,838

 

 

 

 

 

 

 

 

Liabilities, Convertible redeemable preferred stock, and Stockholders' equity

 

 

 

 

 

 

Current Liabilities

 

 

 

 

 

 

Accounts payable

 

 

41,023

 

 

 

81,994

 

Accrued expenses

 

 

160,628

 

 

 

155,370

 

Deferred revenue(2)

 

 

72,866

 

 

 

92,673

 

Deferred other income

 

 

15,955

 

 

 

15,955

 

Other current liabilities

 

 

10,248

 

 

 

8,680

 

Operating lease liabilities

 

 

12,639

 

 

 

13,355

 

Accrued data licensing fees

 

 

4,597

 

 

 

4,361

 

Total current liabilities

 

$

317,956

 

 

$

372,388

 

Operating lease liabilities, less current portion

 

 

72,723

 

 

 

74,272

 

Convertible promissory note

 

 

199,279

 

 

 

208,672

 

Other long-term liabilities

 

 

54,115

 

 

 

56,600

 

Revolving credit facility

 

 

100,000

 

 

 

100,000

 

Interest payable

 

 

15,844

 

 

 

12,393

 

Long-term debt, net

 

 

204,624

 

 

 

202,753

 

Convertible senior notes, net

 

 

729,267

 

 

 

728,078

 

Deferred other income, less current portion

 

 

3,989

 

 

 

7,977

 

Deferred revenue, less current portion

 

 

20,889

 

 

 

20,379

 

Total Liabilities

 

$

1,718,686

 

 

$

1,783,512

 

(1)

Includes related party accounts receivable of $15,690 and $6,428 as of March 31, 2026 and December 31, 2025, respectively.

(2)

Includes related party deferred revenue of $403 and $3,938 as of March 31, 2026 and December 31, 2025, respectively.

 

Tempus AI, Inc.

CONDENSED CONSOLIDATED BALANCE SHEETS

(Unaudited)

(in thousands, except share and per share amounts)

 

Commitments and contingencies (Note 8)

 

 

 

 

 

 

Convertible redeemable preferred stock, $0.0001 par value, 20,000,000 shares authorized at March 31, 2026 and December 31, 2025, respectively, no shares issued and outstanding at March 31, 2026 and December 31, 2025

 

$

 

 

$

 

Stockholders' equity

 

 

 

 

 

 

Class A Common Stock, $0.0001 par value, 1,000,000,000 shares authorized at March 31, 2026 and December 31, 2025, respectively; 174,360,831 and 173,235,428 shares issued and outstanding at March 31, 2026 and December 31, 2025, respectively

 

 

17

 

 

 

17

 

Class B Common Stock, $0.0001 par value, 5,500,000 shares authorized at March 31, 2026 and December 31, 2025, respectively; 5,043,789 issued and outstanding at March 31, 2026 and December 31, 2025, respectively

 

 

1

 

 

 

1

 

Treasury Stock, 183,229 shares at March 31, 2026 and December 31, 2025, respectively, at cost

 

 

(6,642

)

 

 

(6,642

)

Additional Paid-In Capital

 

 

2,945,718

 

 

 

2,892,910

 

Accumulated Other Comprehensive (Loss) Income

 

 

(908

)

 

 

902

 

Accumulated deficit

 

 

(2,521,781

)

 

 

(2,395,862

)

Total Stockholders' equity

 

$

416,405

 

 

$

491,326

 

Total Liabilities, Convertible redeemable preferred stock, and Stockholders' equity

 

$

2,135,091

 

 

$

2,274,838

 

 

Tempus AI, Inc.

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS

(Unaudited)

(in thousands, except per share amounts)

 

 

 

Three Months Ended March 31,

 

 

 

2026

 

 

2025

 

Operating activities

 

 

 

 

 

 

Net loss

 

$

(125,919

)

 

$

(68,037

)

Adjustments to reconcile net loss to net cash used in operating activities

 

 

 

 

 

 

Stock-based compensation

 

 

52,706

 

 

 

22,974

 

Loss on marketable equity securities

 

 

32,309

 

 

 

31,805

 

Loss on disposal of property and equipment

 

 

334

 

 

 

 

Deferred income taxes

 

 

 

 

 

(46,216

)

Losses from equity method investments

 

 

3,086

 

 

 

1,883

 

Amortization of original issue discount

 

 

1,448

 

 

 

560

 

Amortization of deferred financing fees

 

 

86

 

 

 

157

 

Change in fair value of holdback liability

 

 

(1,167

)

 

 

46

 

Depreciation and amortization

 

 

26,175

 

 

 

20,353

 

Provision for bad debt expense

 

 

636

 

 

 

316

 

Provision for obsolete inventory

 

 

225

 

 

 

 

Non-cash operating lease costs

 

 

3,502

 

 

 

2,089

 

Minimum accretion expense

 

 

57

 

 

 

248

 

PIK interest added to principal

 

 

1,674

 

 

 

3,274

 

Change in assets and liabilities

 

 

 

 

 

 

Accounts receivable(1)

 

 

1,990

 

 

 

(45,175

)

Inventory

 

 

(332

)

 

 

(911

)

Prepaid expenses and other current assets

 

 

(2,032

)

 

 

(5,798

)

Investments and other assets

 

 

433

 

 

 

(3,358

)

Accounts payable

 

 

(50,553

)

 

 

23,572

 

Deferred revenue(2)

 

 

(19,297

)

 

 

(12,377

)

Deferred other income

 

 

(3,989

)

 

 

(3,988

)

Accrued data licensing fees

 

 

(6

)

 

 

(250

)

Accrued expenses & other

 

 

5,257

 

 

 

(27,606

)

Interest payable

 

 

3,677

 

 

 

3,508

 

Operating lease liabilities

 

 

(3,577

)

 

 

(2,693

)

Net cash used in operating activities

 

$

(73,277

)

 

$

(105,624

)

(1) Includes increase in related party accounts receivable of $9,262 for the three months ended March 31, 2026. Includes decrease in related party accounts receivable of $3,603 for the three months ended March 31, 2025.

 

(2) Includes decrease in related party deferred revenue of $3,535 for the three months ended March 31, 2026. Includes increase in related party deferred revenue of $300 for the three months ended March 31, 2025.

 

Tempus AI, Inc.

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS

(Unaudited)

(in thousands, except per share amounts)

 

 

 

Three Months Ended March 31,

 

 

 

2026

 

 

2025

 

Investing activities

 

 

 

 

 

 

Purchases of property and equipment

 

$

(8,202

)

 

$

(2,074

)

Proceeds from sale of marketable equity securities

 

 

 

 

 

8,316

 

Business combinations, net of cash acquired (Note 4)

 

 

 

 

 

(380,762

)

Capitalized software costs

 

 

(1,865

)

 

 

(1,298

)

Net cash used in investing activities

 

$

(10,067

)

 

$

(375,818

)

 

 

 

 

 

 

 

Financing activities

 

 

 

 

 

 

Payment of deferred offering costs

 

 

(45

)

 

 

 

Proceeds from revolving credit facility, net of original issue discount

 

 

 

 

 

98,000

 

Proceeds from long-term debt, net of original issue discount

 

 

 

 

 

196,000

 

Payment of deferred financing fees

 

 

(226

)

 

 

(958

)

Net cash (used in) provided by financing activities

 

$

(271

)

 

$

293,042

 

Effect of foreign exchange rates on cash

 

$

28

 

 

$

(109

)

 

 

 

 

 

 

 

Net decrease in Cash, Cash Equivalents and Restricted Cash

 

$

(83,587

)

 

$

(188,509

)

Cash, cash equivalents and restricted cash, beginning of period

 

 

609,451

 

 

 

341,835

 

Cash, cash equivalents and restricted cash, end of period

 

$

525,864

 

 

$

153,326

 

 

 

 

 

 

 

 

Cash, Cash Equivalents and Restricted Cash are Comprised of:

 

 

 

 

 

 

Cash and cash equivalents

 

$

521,170

 

 

$

151,603

 

Restricted cash and cash equivalents

 

 

4,694

 

 

 

1,723

 

Total cash, cash equivalents and restricted cash

 

$

525,864

 

 

$

153,326

 

 

 

 

 

 

 

 

Supplemental disclosure of cash flow information

 

 

 

 

 

 

Cash paid during the year for interest

 

$

9,322

 

 

$

10,849

 

Cash (received from) paid for income taxes

 

$

(56

)

 

$

 

 

 

 

 

 

 

 

Supplemental disclosure of noncash investing and financing activities

 

 

 

 

 

 

Purchases of property and equipment, accrued but not paid

 

$

4,592

 

 

$

7,003

 

Redemption of convertible promissory note

 

$

9,393

 

 

$

7,060

 

Capitalized software costs, accrued but not yet paid

 

$

2,129

 

 

$

 

Deferred offering costs, accrued but not yet paid

 

$

100

 

 

$

 

Class A Common Stock issued in connection with business combinations

 

$

 

 

$

310,320

 

Convertible promissory note principal reset due to amendment

 

$

 

 

$

72,488

 

 

Tempus AI, Inc.

RECONCILIATION OF GAAP TO NON-GAAP FINANCIAL MEASURES

(Unaudited)

(in thousands, except percentages and per share amounts)

 

Diagnostics Gross Profit & Gross Margin

 

 

 

Three Months Ended March 31,

 

 

 

2026

 

 

2025

 

Diagnostics revenue

 

$

261,098

 

 

$

193,804

 

Cost of revenues, diagnostics

 

 

100,960

 

 

 

84,783

 

Gross profit, diagnostics

 

$

160,138

 

 

$

109,021

 

Stock-based compensation expense

 

 

2,122

 

 

 

1,035

 

Employer payroll tax related to stock-based compensation

 

 

334

 

 

 

48

 

Non-GAAP gross profit, diagnostics

 

$

162,594

 

 

$

110,104

 

Diagnostics gross margin

 

 

61.3

%

 

 

56.3

%

Stock-based compensation expense

 

 

0.8

%

 

 

0.5

%

Employer payroll tax related to stock-based compensation

 

 

0.1

%

 

 

0.0

%

Non-GAAP gross margin, diagnostics

 

 

62.3

%

 

 

56.8

%

Data and applications Gross Profit & Gross Margin

 

 

 

Three Months Ended March 31,

 

 

 

2026

 

 

2025

 

Data and applications revenue

 

$

87,018

 

 

$

61,933

 

Cost of revenues, data and applications

 

 

25,115

 

 

 

15,751

 

Gross profit, data and applications

 

$

61,903

 

 

$

46,182

 

Stock-based compensation expense

 

 

1,553

 

 

 

611

 

Employer payroll tax related to stock-based compensation

 

 

184

 

 

 

44

 

Non-GAAP gross profit, data and applications

 

$

63,640

 

 

$

46,837

 

Gross margin, data and applications

 

 

71.1

%

 

 

74.6

%

Stock-based compensation expense

 

 

1.8

%

 

 

1.0

%

Employer payroll tax related to stock-based compensation

 

 

0.2

%

 

 

0.1

%

Non-GAAP gross margin, data and applications

 

 

73.1

%

 

 

75.6

%

 

Total Gross Profit & Gross Margin

 

 

 

Three Months Ended March 31,

 

 

 

2026

 

 

2025

 

Net revenue

 

$

348,116

 

 

$

255,737

 

Cost of revenues

 

 

126,075

 

 

 

100,534

 

Gross profit

 

$

222,041

 

 

$

155,203

 

Stock-based compensation expense

 

 

3,675

 

 

 

1,646

 

Employer payroll tax related to stock-based compensation

 

 

518

 

 

 

91

 

Non-GAAP gross profit

 

$

226,234

 

 

$

156,940

 

Gross margin

 

 

63.8

%

 

 

60.7

%

Stock-based compensation expense

 

 

1.1

%

 

 

0.6

%

Employer payroll tax related to stock-based compensation

 

 

0.1

%

 

 

0.0

%

Non-GAAP gross margin

 

 

65.0

%

 

 

61.4

%

 

Operating Expenses

 

 

 

Three Months Ended March 31,

 

 

 

2026

 

 

2025

 

Technology research and development

 

$

45,921

 

 

$

33,391

 

Stock-based compensation expense

 

 

9,506

 

 

 

3,319

 

Employer payroll tax related to stock-based compensation

 

 

812

 

 

 

261

 

Non-GAAP technology research and development

 

$

35,603

 

 

$

29,811

 

Research and development

 

$

48,237

 

 

$

35,874

 

Stock-based compensation expense

 

 

4,565

 

 

 

1,982

 

Employer payroll tax related to stock-based compensation

 

 

483

 

 

 

176

 

Non-GAAP research and development

 

$

43,189

 

 

$

33,716

 

Selling, general and administrative

 

$

212,594

 

 

$

154,627

 

Stock-based compensation expense

 

 

34,960

 

 

 

16,027

 

Employer payroll tax related to stock-based compensation

 

 

1,745

 

 

 

4,725

 

Acquisition related expenses(1)

 

 

(4

)

 

 

3,529

 

Amortization of intangibles due to acquisition

 

 

16,871

 

 

 

11,156

 

Non-GAAP selling, general and administrative

 

$

159,022

 

 

$

119,190

 

Operating expenses

 

$

306,752

 

 

$

223,892

 

Stock-based compensation expense

 

 

49,031

 

 

 

21,328

 

Employer payroll tax related to stock-based compensation

 

 

3,040

 

 

 

5,162

 

Acquisition related expenses(1)

 

 

(4

)

 

 

3,529

 

Amortization of intangibles due to acquisition

 

 

16,871

 

 

 

11,156

 

Non-GAAP operating expenses

 

$

237,814

 

 

$

182,717

 

(1)

Acquisition related expenses consist of legal, diligence, accounting, and financing costs incurred for acquisitions during the three months ended March 31, 2026 and 2025.

 

Loss from Operations

 

 

 

Three Months Ended March 31,

 

 

 

2026

 

 

2025

 

Loss from operations

 

$

(84,711

)

 

$

(68,689

)

Stock-based compensation expense

 

 

52,706

 

 

 

22,974

 

Employer payroll tax related to stock-based compensation

 

 

3,558

 

 

 

5,253

 

Acquisition related expenses(1)

 

 

(4

)

 

 

3,529

 

Amortization of intangibles due to acquisition

 

 

16,871

 

 

 

11,156

 

Non-GAAP loss from operations

 

$

(11,580

)

 

$

(25,777

)

(1)

Acquisition related expenses consist of legal, diligence, accounting, and financing costs incurred for acquisitions during the three months ended March 31, 2026 and 2025.

 

Earnings per Share

 

 

 

Three Months Ended March 31,

 

 

 

2026

 

 

2025

 

Net loss

 

$

(125,919

)

 

$

(68,037

)

Fair value changes(1)

 

 

31,141

 

 

 

31,850

 

Stock-based compensation expense

 

 

52,706

 

 

 

22,974

 

Employer payroll tax related to stock-based compensation

 

 

3,558

 

 

 

5,253

 

Acquisition related expenses(2)

 

 

(4

)

 

 

3,529

 

Amortization of intangibles due to acquisition

 

 

16,871

 

 

 

11,156

 

Losses from equity method investments

 

 

3,086

 

 

 

1,883

 

Benefit from income taxes

 

 

(62

)

 

 

(46,180

)

Amortization of technology license

 

 

(3,989

)

 

 

(3,989

)

Non-GAAP net loss

 

$

(22,612

)

 

$

(41,561

)

Non-GAAP net loss per share, basic

 

$

(0.13

)

 

$

(0.24

)

Weighted average common shares outstanding, basic

 

 

178,880

 

 

 

170,506

 

(1)

Fair value changes include gains and losses related to quarterly fair value adjustments of our marketable equity securities and indemnity-related holdback liabilities. 

(2)

Acquisition related expenses consist of legal, diligence, accounting, and financing costs incurred for acquisitions during the three months ended March 31, 2026 and 2025.

 

Adjusted EBITDA

 

 

 

Three Months Ended March 31,

 

 

 

2026

 

 

2025

 

Net loss

 

$

(125,919

)

 

$

(68,037

)

Interest income

 

 

(3,866

)

 

 

(1,813

)

Interest expense

 

 

14,341

 

 

 

18,003

 

Depreciation

 

 

7,425

 

 

 

7,883

 

Amortization

 

 

18,750

 

 

 

12,470

 

Benefit from income taxes

 

 

(62

)

 

 

(46,180

)

EBITDA

 

$

(89,331

)

 

$

(77,674

)

Losses from equity method investments

 

 

3,086

 

 

 

1,883

 

Fair value changes(1)

 

 

31,141

 

 

 

31,850

 

Stock-based compensation expense

 

 

52,706

 

 

 

22,974

 

Employer payroll tax related to stock-based compensation

 

 

3,558

 

 

 

5,253

 

Acquisition related expenses(2)

 

 

(4

)

 

 

3,529

 

Amortization of technology license

 

 

(3,989

)

 

 

(3,989

)

Adjusted EBITDA

 

$

(2,833

)

 

$

(16,174

)

(1)

Fair value changes include gains and losses related to quarterly fair value adjustments of our marketable equity securities and indemnity-related holdback liabilities. 

(2)

Acquisition related expenses consist of legal, diligence, accounting, and financing costs incurred for acquisitions of during the three months ended March 31, 2026 and 2025.

 

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